Anti-Mouse CD72.1/Lyb-2.1-UNLB

Murine CD72.1/Lyb-2.1, a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells, and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 (Ly-1) which is distributed on all T cells and a small number of B cells. The 10-1.D.2 monoclonal antibody blocks binding of CD5 to CD72 on the B cell surface, which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. However, 10-1.D.2 can itself trigger a positive signal by binding CD72.

Product Specifications

CAS Number

9007-83-4

Reactivity

Mouse

Immunogen

DBA/2 mouse spleen cells

Clonality

Monoclonal

Type

Antibodies-Monoclonal

Applications

Flow cyt

Concentration

100ug/200ul

Purity

Affinity purified

Buffer

PBS, pH 7.4 with 0.05% sodium azide.

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.