Anti-Mouse CD11c (Alexa Fluor 488)

CD11c is a 150 kD glycoprotein, also known as βX integrin, CR4, or p150. CD11c forms a βXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The βXβ2 integrin plays an important role in cell-cell contact by binding its ligands, iC3b, fibrinogen, and CD54.

Product Specifications

Reactivity

Mouse

Immunogen

The antibody was purified by affinity chromatography, and conjugated with Alexa FluorÂ® 488 under optimal conditions. The solution is free of unconjugated Alexa FluorÂ® 488.

Clonality

Monoclonal

Clone

Monoclonal [N418]

Type

Antibodies-Monoclonal

Applications

IHC,ICC/IF,Flow cyt

Purity

The antibody was purified by affinity chromatography, and conjugated with Alexa FluorÂ® 488 under optimal conditions. The solution is free of unconjugated Alexa FluorÂ® 488.

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Fragment

IgG

Applications Notes

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is â‰¤ 0.25 µg per 106 cells in 100 Âµl volume. It is recommended that the reagent be titrated for optimal performance for other applications.