Anti-M-cadherin

This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis,and may provide a trigger for terminal muscle cell differentiation.

Product Specifications

CAS Number

9007-83-4

Reactivity

Human

Immunogen

peptide from the intermediate residues of human M-cadherin protein.

Clonality

Polyclonal

Type

Antibodies-Polyclonal

Applications

ELISA

Concentration

100ug/100ul

Purity

Peptide affinity purified

Buffer

PBS, pH 7.4 with 0.02% Sodium Azide

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Specificity

M-cadherin antibody detects endogenous levels of M-cadherin protein. Not tested with other proteins

Applications Notes

Recommended dilutions ELISA: 1:20,000 WB: 1/200 - 1/1000 IHC:1/100-1/500Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user