Anti-MAD1
Mad1 negatively regulates mitosis by preventing cells with misaligned chromosomes from dividing. It is an important target in cancer research because it may sensitize cells to existing chemotherapeutics and its expression may be an indicator of cellular sensitivity to chemotherapy. Mad 1is known to repress Myc target genes and antagonize Myc function.
Product Specifications
CAS Number
9007-83-4
Immunogen
Recombinant human Mad1
Clonality
Monoclonal
Clone
P22.9B10.C12
Type
Antibodies-Monoclonal
Applications
WB,IP,ICC/IF
Concentration
100ug/100ul
Purity
Purified ascites.
Buffer
PBS, pH 7.4 with 0.02% sodium azide.
Shipping Conditions
Ice Pack
Storage Conditions
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Fragment
IgG2b
Specificity
Reacts with human Mad1; other species specificity has not yet been determined
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