Anti-JAK2 (Phospho-Tyr221)
This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008]
Product Specifications
Reactivity
Human,Mouse,Rat
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human JAK2 around the phosphorylation site of tyrosine 221 (Q-D-YP-H-I).
Clonality
Polyclonal
Type
Antibodies-Polyclonal
Applications
IHC
Concentration
1ug/ul
Purity
Buffer
phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Shipping Conditions
Ice Pack
Storage Conditions
Specificity
JAK2 (phospho-Tyr221) antibody detects endogenous levels of JAK2 only when phosphorylated at tyrosine 221.
Applications Notes
IHC: 1:50~1:100
CAS Number
9007-83-4
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