Anti-HIRA
HIRA is the human homologue of two cell cycle-regulated repressors of histone gene expression in Saccharomyces cerevisiae, Hir1p and Hir2p. In yeast, Hir1p and Hir2p control histone gene expression through the cell cycle. In human cells, HIRA contributes to formation of transcriptionally-repressive heterochromatin in senescent cells and also has roles in transcription-coupled chromatin assembly.
Product Specifications
CAS Number
9007-83-4
Reactivity
Human
Immunogen
Glutathione S-transferase-HIRA [421-729] (human HIRA)
Clonality
Monoclonal
Clone
WC119.2H11
Type
Antibodies-Monoclonal
Applications
WB
Concentration
100ug/100ul
Purity
Purified ascites.
Buffer
PBS, pH 7.4 with 0.02% sodium azide.
Shipping Conditions
Ice Pack
Storage Conditions
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Fragment
IgG1
Specificity
Reacts with human HIRA.
Applications Notes
Titrate for optimal conditions for your specific application.
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