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Anti-CPI17β (Ab-38)

PKC potentiated inhibitor protein-17 is a 17kDa protein. Expressed in smooth muscles and neuronal cells, CP117 is a myosin phosphatase inhibitor protein. Phosphorylation of CP117 at Thr38 enhances its inhibitory effect by 100 fold. Once phosphorylated, CP117 inhibits PP1c and MLCP holoenzyme activity.

Product Specifications

Reactivity

Human,Mouse,Rat

Immunogen

The antiserum was produced against synthesized non-phosphopeptide derived from human CPI17β around the phosphorylation site of threonine 38 (R-V-T[P]-V-K).

Clonality

Polyclonal

Type

Antibodies-Polyclonal

Applications

ICC/IF

Concentration

100ug/100ul

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Buffer

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Fragment

IgG

Specificity

CPI17β (Ab-38) antibody detects endogenous levels of total CPI17β protein.

CAS Number

9007-83-4

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