Anti-CPI17β (Ab-38)
PKC potentiated inhibitor protein-17 is a 17kDa protein. Expressed in smooth muscles and neuronal cells, CP117 is a myosin phosphatase inhibitor protein. Phosphorylation of CP117 at Thr38 enhances its inhibitory effect by 100 fold. Once phosphorylated, CP117 inhibits PP1c and MLCP holoenzyme activity.
Product Specifications
CAS Number
9007-83-4
Reactivity
Human,Mouse,Rat
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human CPI17β around the phosphorylation site of threonine 38 (R-V-T[P]-V-K).
Clonality
Polyclonal
Type
Antibodies-Polyclonal
Applications
ICC/IF
Concentration
100ug/100ul
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Shipping Conditions
Ice Pack
Storage Conditions
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Fragment
IgG
Specificity
CPI17β (Ab-38) antibody detects endogenous levels of total CPI17β protein.
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