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Anti-CD8

CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/ suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck.

Product Specifications

CAS Number

9007-83-4

Reactivity

Human

Immunogen

Ni-NTA purified recombinant human CD8 expressed in E. Coli strain BL21 (DE3).

Clonality

Monoclonal

Type

Antibodies-Monoclonal

Applications

WB,IHC,ELISA

Concentration

1ug/ul

Purity

purified by protein A affinity chromatography.

Buffer

PBS, pH 7.4 with 0.05% sodium azide.

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Fragment

IgG1

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