Anti-ASAH3(N-acylsphingosine amidohydrolase 3)
ASAH3(N-acylsphingosine amidohydrolase 3) or CER1(alkaline ceramidase) deacylates ceramide to generate sphingosine and a fatty acid. Ceramidases deacylate ceramides, important intermediates in the metabolic pathway of sphingolipids. CER1 is selectively expressed in skin and may have a role in regulating the levels of bioactive lipids ceramide and S1P, as well as complex sphingolipids.
Product Specifications
CAS Number
9007-83-4
Reactivity
Human
Immunogen
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human ASAH3(N-acylsphingosine amidohydrolase
3) or CER1(alkaline ceramidase)
Clonality
Polyclonal
Type
Antibodies-Polyclonal
Applications
WB,ELISA
Concentration
1ug/ul
Purity
Purified by antigen-specific affinity chromatography.
Buffer
PBS, pH 7.4 with 0.05% sodium azide.
Shipping Conditions
Ice Pack
Storage Conditions
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Fragment
IgG
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