Anti-ABL1/2 (Ab-393/429)

This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009]

Product Specifications

Reactivity

Human,Mouse

Immunogen

The antibody was produced against synthesized non-phosphopeptide derived from human ABL1/2 around the phosphorylation site of tyrosine 393/429 (D-T-YP-T-A).

Clonality

Polyclonal

Type

Antibodies-Polyclonal

Applications

IHC,IP

Concentration

100ug/100ul

Purity

Affinity purified

Buffer

Rabbit IgG in phosphate buffered saline (without Mg<sup>2</sup>+and Ca<sup>2</sup>+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.