SensiStain™ Anti-CDK4 Antibody
CDK4 controls cell growth during the cell cycle G1 phase. It is reported that D-type cyclin upregulates Cdk4 activity, whereas binding to the Cdk inhibitor p16 downregulates Cdk4 activity. Cyclin D-CDK4 complexes integrates various mitogenenic and antimitogenic signals and serves as sensitive and specific for atypical lipomatous tumor / well differentiated liposarcoma or dedifferentiated liposarcoma.
Product Specifications
CAS Number
9007-83-4
Reactivity
Human
Immunogen
Recombinant Protein
Clonality
Monoclonal
Clone
IHC077
Type
Antbodies-IHC
Applications
ELISA, IHC
Purity
Purified
Buffer
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Shipping Conditions
Ice Pack
Storage Conditions
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Fragment
IgG
Specificity
CDK4
Applications Notes
1:50-1:200
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