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SensiStain™ Anti-Perforin Antibody

Perforin, a pore-forming protein found in the granules of cytotoxic T-lymphocytes and natural killer cells, functions to enable granzymes to enter the target cells and activate apoptosis. It has been suggested that perforin plays a role in alloimmunity, being involved in both the cytolytic process of rejection as well as downregulation of the T-cell mediated responses associated with the alloimmune response. Perforin-mediated cytotoxicity has also been linked to a number of autoimmune diseases.

Product Specifications

CAS Number

9007-83-4

Reactivity

Human

Immunogen

Recombinant Protein

Clonality

Monoclonal

Clone

IHC646

Type

Antbodies-IHC

Applications

ELISA, IHC

Purity

Purified

Buffer

Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Fragment

IgG2c

Specificity

Perforin

Applications Notes

1:50-1:200

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