SensiStain™ Anti-PD-L1 Antibody
Programmed Death-Ligand 1 (PD-L1), CD274, or B7 Homolog 1 (B7-H1), is a transmembrane protein involved in suppressing the immune system and rendering tumour cells resistant to lysis through binding of the Programmed Death-1 (PD-1) receptor. Overexpression of PD-L1 may allow cancer cells to evade the actions of the host immune system. In renal cell carcinoma, upregulation of PD-L1 has been linked to increased tumour aggressiveness and risk of death.
Product Specifications
CAS Number
9007-83-4
Reactivity
Human
Immunogen
Recombinant Protein
Clonality
Monoclonal
Clone
IHC411
Type
Antbodies-IHC
Applications
ELISA, IHC
Purity
Purified
Buffer
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Shipping Conditions
Ice Pack
Storage Conditions
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Fragment
IgG
Specificity
PD-L1
Applications Notes
1:50-1:200
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