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SensiStain™ Anti-BCL2 Antibody

B-Cell Lymphoma 2 (BCL2) is involved in regulation of cell apoptosis by controlling mitochondrial permeability and release of cytochrome c. It also has critical roles in normal cell physiology related to neuronal activity, autophagy, calcium handling, mitochondrial dynamics, and energetics. BCL2 overexpression has been shown to promote cell survival by suppressing apoptosis, and is found to be correlated with poor disease prognosis in breast, prostate, ovarian, endometrial, and colon cancers.

Product Specifications

CAS Number

9007-83-4

Reactivity

Human

Immunogen

Recombinant Protein

Clonality

Monoclonal

Clone

IHC514

Type

Antbodies-IHC

Applications

ELISA, IHC

Purity

Purified

Buffer

Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Fragment

IgG1

Specificity

BCL2

Applications Notes

1:50-1:200

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