SensiStain™ Anti-BCL2 Antibody
B-Cell Lymphoma 2 (BCL2) is involved in regulation of cell apoptosis by controlling mitochondrial permeability and release of cytochrome c. It also has critical roles in normal cell physiology related to neuronal activity, autophagy, calcium handling, mitochondrial dynamics, and energetics. BCL2 overexpression has been shown to promote cell survival by suppressing apoptosis, and is found to be correlated with poor disease prognosis in breast, prostate, ovarian, endometrial, and colon cancers.
Product Specifications
Reactivity
Human
Immunogen
Recombinant Protein
Clonality
Monoclonal
Clone
IHC514
Type
Antbodies-IHC
Applications
ELISA, IHC
Purity
Purified
Buffer
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Shipping Conditions
Ice Pack
Storage Conditions
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Fragment
IgG1
Specificity
BCL2
Applications Notes
1:50-1:200
CAS Number
9007-83-4
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