6-O-Caffeoylarbutin
6-O-Caffeoylarbutin (Robustaside B) possesses antioxidant activity[1]. 6-O-Caffeoylarbutin ameliorates neurological functions and deficits in ischemic mice.
Product Specifications
CAS Number
136172-60-6
Product Name Alternative
Robustaside B
UNSPSC
12352005
Target
PI3K; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/6-o-caffeoylarbutin.html
Purity
99.47
Solubility
10 mM in DMSO
Smiles
OC(C=C1/C=C/C(OC[C@H]([C@H]([C@@H]([C@H]2O)O)O)O[C@H]2OC3=CC=C(C=C3)O)=O)=C(C=C1)O
Molecular Formula
C21H22O10
Molecular Weight
434.39
References & Citations
[1]Rahmat A Adisa, et al. Robustaside B and para‑hydroxyphenol: phenolic and antioxidant compounds purified from Cnestis ferruginea D.C induced membrane permeability transition in rat liver mitochondria. Mol Med Rep. 2013 Nov;8 (5) :1493-8.|[2]Shi ZQ, Wen X, Wu XR, et al. 6'-O-caffeoylarbutin of Vaccinium dunalianum alleviated ischemic stroke through the PI3K/AKT/NF-κB pathway. Phytomedicine. 2025;139:156505. |[3]Wang Y, Wang Y, Zhao T, et al. 6'-O-caffeoylarbutin attenuates D-galactose-induced brain and liver damage in aging mice via regulating SIRT1/NF-κB pathway. Phytomedicine. 2025;141:156710. |[4]Wang YP, Wang YD, Liu YP, et al. 6'-O-Caffeoylarbutin from Que Zui tea ameliorates acetaminophen-induced liver injury via enhancing antioxidant ability and regulating the PI3K signaling pathway. Food Funct. 2022;13 (9) :5299-5316.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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