1- (1-Naphthyl) piperazine (hydrochloride)
1-1-Naphthylpiperazine hydrochloride (1-NP hydrochloride; 1-Naphthylpiperazine hydrochloride) is a serotonergic derivative of quipazine, which is both an agonist for 5-HT1A receptor and an antagonist for 5-HT2A receptor. 1-1-Naphthylpiperazine hydrochloride induces cell apoptosis. 1-1-Naphthylpiperazine hydrochloride prevents the immunosuppression and photocarcinogenesis[1].
Product Specifications
CAS Number
104113-71-5
Product Name Alternative
1-NP (hydrochloride) ; 1-Naphthylpiperazine (hydrochloride)
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
5-HT Receptor; Apoptosis
Type
Reference compound
Related Pathways
Apoptosis; GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/1-1-naphthyl-piperazine-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
C12=C(C=CC=C2N3CCNCC3)C=CC=C1.Cl
Molecular Formula
C14H17ClN2
Molecular Weight
248.75
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor;5-HT2 Receptor; mLAG-3; α-1 microglobulin
Available Sizes
Frequently Asked Questions
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