Triclabendazole sulfoxide (Standard)

Triclabendazole sulfoxide (Standard) is the analytical standard of Triclabendazole sulfoxide. This product is intended for research and analytical applications. Triclabendazole sulfoxide (TCBZ-SO) is the main plasma metabolite of Triclabendazole, and exhibits anti-parasite effects. Triclabendazole sulfoxide can inhibit membrane transporter ABCG2/BCRP[1][2].

Product Specifications

CAS Number

[100648-13-3]

Product Name Alternative

TCBZ-SO (Standard)

UNSPSC

12352005

Target

BCRP; Parasite; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Membrane Transporter/Ion Channel; Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/triclabendazole-sulfoxide-standard.html

Smiles

O=S(C1=NC2=CC(OC3=CC=CC(Cl)=C3Cl)=C(Cl)C=C2N1)C

Molecular Formula

C14H9Cl3N2O2S

Molecular Weight

375.66

References & Citations

[1]Barrera B, et, al. The anthelmintic triclabendazole and its metabolites inhibit the membrane transporter ABCG2/BCRP. Antimicrob Agents Chemother. 2012 Jul;56 (7) :3535-43.|[2]Robinson MW, et, al. The comparative metabolism of triclabendazole sulphoxide by triclabendazole-susceptible and triclabendazole-resistant Fasciola hepatica. Parasitol Res. 2004 Feb;92 (3) :205-10.