Triclabendazole sulfoxide (Standard)
Product Specifications
UNSPSC Description
Triclabendazole sulfoxide (Standard) is the analytical standard of Triclabendazole sulfoxide. This product is intended for research and analytical applications. Triclabendazole sulfoxide (TCBZ-SO) is the main plasma metabolite of Triclabendazole, and exhibits anti-parasite effects. Triclabendazole sulfoxide can inhibit membrane transporter ABCG2/BCRP[1][2].
Target Antigen
BCRP; Parasite
Type
Reference Standards
Related Pathways
Anti-infection;Membrane Transporter/Ion Channel
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/triclabendazole-sulfoxide-standard.html
Smiles
O=S(C1=NC2=CC(OC3=CC=CC(Cl)=C3Cl)=C(Cl)C=C2N1)C
Molecular Weight
375.66
References & Citations
[1]Barrera B, et, al. The anthelmintic triclabendazole and its metabolites inhibit the membrane transporter ABCG2/BCRP. Antimicrob Agents Chemother. 2012 Jul;56(7):3535-43.|[2]Robinson MW, et, al. The comparative metabolism of triclabendazole sulphoxide by triclabendazole-susceptible and triclabendazole-resistant Fasciola hepatica. Parasitol Res. 2004 Feb;92(3):205-10.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-136450R/Triclabendazole-sulfoxide-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-136450R/
CAS Number
100648-13-3
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