Recombinant Rat LIX (CXCL5)
Epithelial neutrophil-activating protein 78 (ENA-78) is a member of the CXC chemokines and acts as a potent chemoattractant and activator of neutrophil function. On stimulation in vitro, ENA-78 is highly expressed in many cell types. ENA-78 protein levels are strongly elevated in synovial fluid and blood of patients with rheumatoid arthritis. By in situ hybridization and immunofluorescence staining, ENA-78 has been recognized as a major CXC chemokine expressed in epithelial cells of the intestinal mucosa of patients with Crohn's disease, ulcerative colitis, and acute appendicitis.
Product Specifications
Gene Name
CXCL5
Gene Aliases
Cytokine LIX, Small-inducible cytokine B5, C-X-C motif chemokine 5
Gene ID
60665
Accession Number
P97885
Organism
Rat
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
Function
Determined by its ability to chemoattract human neutrophils using a concentration range of 2.0-40.0 ng/mL.
Molecular Weight
11
Shipping Conditions
Ambient Temperature
Storage Conditions
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 µm filtered solution in PB, 100 mM NaCl, pH 7.5.
CAS Number
9000-83-3
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