Recombinant Rat IL20
IL-19 and IL-20 are mainly produced by activated monocytes , IL-24 is produced by Th2 cells, monocytes, and melanocytic cells , and IL-22 and IL-26 are primarily produced by activated T cells. Like IL-10, these class II cytokines signal through heterodimeric receptors. Overexpression of IL-20 in transgenic mice causes neonatal death as well as skin abnormalities, including aberrant epidermal differentiation. IL-20 selectively enhances multipotential hematopoietic progenitors in vitro and in vivo. IL-20 is preferentially expressed in monocytes18 and induces STAT 3 activation through binding to 2 types of IL-20 receptor (R) complexes, either IL- 20R1/IL-20R2 or IL-22R1/IL- 20R2
Product Specifications
CAS Number
9000-83-3
Gene Name
IL20
Gene Aliases
IL-20<br/>Recombinant Rat Interleukin-20 (IL20)
Gene ID
681112
Accession Number
B8K1Y1
Organism
Rat
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
Function
Molecular Weight
16
Shipping Conditions
Ambient Temperature
Storage Conditions
Appearance
Lyophilized Powder
Formulation
Recombinant Rat Interleukin-20 was lyophilized from a 0.2 μm filtered PBS solution pH 7.5.
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