Recombinant Rat IL2
Rat IL2, also known as T-cell growth factor, is a secreted immunoregulatory cytokine produced by T-cells due to antigenic or mitogenic stimulation. IL2 binds to the IL2 receptor, which is found in T and B cells and natural killer cells, and is composed of three distinct components: the cytokine specific α-chain, and the β– and γc-subunits. Its receptor complex IL2 induces the proliferation of T cells, generation of cytotoxic T lymphocytes (CTLs), proliferation and synthesis of immunoglobulin by B cells, and the survival of natural killer cells. Its heterotrimeric receptor complex is also shared by Interleukin 4 (IL4) and Interleukin 7 (IL7) by its gamma chain, and receptor signalling is essential for its expression and differentiation of regulatory T cells in the immune response.
Product Specifications
CAS Number
9000-83-3
Gene Name
IL2
Gene Aliases
T-cell growth factor
Gene ID
116562
Accession Number
P17108
Organism
Rat
Source
E. coli
Concentration
< 1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Function
The ED50 was 0.04-0.2 ng/mL as determined by a cell proliferation assay
Molecular Weight
15.6
Shipping Conditions
Ambient Temperature
Storage Conditions
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 µm filtered solution in ammonium acetate and glycerol (with BSA as a carrier protein)
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
