What is the catalog number for Recombinant Rat IGF1?

The catalog number for Recombinant Rat IGF1 is Z300057.

What sizes are available for Recombinant Rat IGF1?

Recombinant Rat IGF1 is available in the following size(s): 250 µg.

Is Recombinant Rat IGF1 in stock?

Recombinant Rat IGF1 is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant Rat IGF1

Insulin-like growth factor I, also known as somatomedin C, is the dominant effector of growth hormone and is structurally homologous to proinsulin. Human IGF-I is synthesized as two precursor isoforms with N- and alternate C- terminal propeptides (1). These isoforms are differentially expressed by various tissues (1). The 7.6 kDa mature IGF-I is identical between isoforms and is generated by proteolytic removal of the N- and C- terminal regions. Mature human IGF-I shares 94% and 96% aa sequence identity with mouse and rat IGF-I, respectively (2), and exhibits cross-species activity. It shares 64% aa sequence identity with mature human IGF-II. Circulating IGF-I is produced by hepatocytes, while local IGF-I is produced by many other tissues in which it has paracrine effects.

Product Specifications

CAS Number

9000-83-3

Gene Name

IGF1

Gene Aliases

Somatomedin, Insulin-like growth factor I, IGF-I, Igf1<br/>Recombinant Rat Insulin-Like Growth Factor (IGF1)

Gene ID

24482

Accession Number

P08025

Organism

Rat

Source

E. coli

Concentration

< 1.0 EU/μg of recombinant protein as determined by the LAL method.

Purity

>95% as determined by SDS-PAGE

Solubility

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Function

The ED(50) was determined by a cell proliferation assay using FDC-P1 cells is ≤ 1.0 ng/mL, corresponding to a specific activity of ≥ 1.0 x 10^6 units/mg.

Molecular Weight

8

Shipping Conditions

Ambient Temperature

Storage Conditions

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.