Recombinant Porcine LIF

LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation. It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL6 family of cytokines, which also includes IL11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1. The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130.

Product Specifications

CAS Number

9000-83-3

Gene Name

LIF

Gene Aliases

LIF, Differentiation-stimulating factor, D factor, Melanoma-derived LPL inhibitor (MLPLI) Recombinant Porcine Leukemia Inhibitory Factor (LIF)

Gene ID

399503

Accession Number

Q9GKZ8

Organism

Rat

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method

Purity

>95% as determined by SDS-PAGE

Solubility

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Molecular Weight

Shipping Conditions

Ambient Temperature

Storage Conditions

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favourable performance, avoid repeated handling and multiple freeze/thaw cycles.