Recombinant Mouse MCP-5 (CCL12)

MCP-5 (CCL12) is a chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. It is also a potent active monocyte chemokine that signals through CCR2. It is Involved in allergic inflammation and the host response to pathogens. Also, it may play a pivotal role during early stages of allergic lung inflammation.

Product Specifications

CAS Number

9000-83-3

Gene Name

CCL12

Gene Aliases

MCP-1-related chemokine, Monocyte chemotactic protein 5, MCP5, Small-inducible cytokine A12, C-C motif chemokine 12, Mcp5, Scya12 <br/>Recombinant Mouse Monocyte Chemoattractant Protein-5 (CCL12)

Gene ID

20293

Accession Number

Q62401

Organism

Mouse

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Purity

>95% as determined by SDS-PAGE

Solubility

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Function

Determined by its ability to chemoattract human monocytes using a concentration range of 20-40 ng/mL.

Molecular Weight

Shipping Conditions

Ambient Temperature

Storage Conditions

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.