What is the catalog number for Recombinant Human WNT1?

The catalog number for Recombinant Human WNT1 is Z102125.

What sizes are available for Recombinant Human WNT1?

Recombinant Human WNT1 is available in the following size(s): 10 µg.

Is Recombinant Human WNT1 in stock?

Recombinant Human WNT1 is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant Human WNT1

Wnt-1 is a secreted protein that signals through the frizzled family of seven transmembrane receptors. Wnt-1 activation induces a complex signaling cascade that ultimately leads to the up-regulation of over fifty genes. Stabilization and resulting accumulation of the intracellular signaling protein β-catenin is an important aspect of Wnt-1 signaling. While known to play in role as a developmental protein, elevated levels of Wnt proteins have also been associated with tumorigenesis.

Product Specifications

CAS Number

9000-83-3

Gene Name

WNT1

Gene Aliases

Proto-oncogene Int-1 homolog, Wnt-1<br/>Recombinant Human Proto-oncogene Wnt-1 (WNT1)

Gene ID

7471

Accession Number

P04628

Organism

Human

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method

Purity

>95% as determined by SDS-PAGE

Solubility

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1 - 1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (0.1% BSA) and store in working aliquots at -20 to -80⁰C

Function

Determined by its ability to enhance BMP-2 induced alkaline phosphatase production by murine ATDC5 cells. The expected ED50 for this effect is 1.5 - 2.5 ng/ml in the presence of 200ng/ml of human BMP-2.

Molecular Weight

38.5

Shipping Conditions

Ambient Temperature

Storage Conditions

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.