Recombinant Human TNFRSF1B
TNFRSF1B is a single-pass type-1 transmembrane protein that functions as a receptor with high affinity for TNFSF2/TNF-alpha . It has been shown that signaling through this receptor regulates various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. Recombinant human TNFRSF1B comprises the extracellular domain (ligand binding) of the TNFRII protein.
Product Specifications
CAS Number
9000-83-3
Gene Name
TNFRSF1B
Gene Aliases
Gene ID
7133
Accession Number
P20333
Organism
Human
Source
E. coli
Concentration
< 1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
Reconstitute at 0.1mg/mL in sterile PBS.
Function
The ED(50) was determined by the dose-dependent proliferation of Immortalized human renal proximal tubule cells and was found to be <0.05ng/mL.
Molecular Weight
19
Shipping Conditions
Ambient Temperature
Storage Conditions
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS.
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