Recombinant Human TGFA
An EGF family member, TGF-A is a cytokine that is produced following the protease digestion of its trans-membrane precursor proTGF-A. TGF-A is expressed both in normal tissues during embryogenesis and in adult tissues, such as the brain, keratinocytes, and macrophages and at high levels in transformed and tumour cells.
Product Specifications
Gene Name
TGFA
Gene Aliases
TGF-alpha, TGF-A, isoform CRA_d<br/>Recombinant Human Transforming Growth Factor Alpha (TGFA)
Gene ID
7039
Accession Number
P01135
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
Reconstitute at 100 μg/mL in sterile 10 mM Acetic Acid
Function
Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED(50) for this effect is typically 0.10.4 ng/mL.
Molecular Weight
5.8
Shipping Conditions
Ambient Temperature
Storage Conditions
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA
CAS Number
9000-83-3
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