Recombinant Human TFF3

Found in the gastrointestinal tract, the three Trefoil proteins, TFF1, 2, and 3 have been shown to play an important role in intestinal mucosal defence and repair. In addition to being expressed by goblet cells and in the uterus, TFF3 has also been shown to express in certain cancers providing a potential use as a molecular marker for those cancers.

Product Specifications

CAS Number

9000-83-3

Gene Name

TFF3

Gene Aliases

Intestinal trefoil factor, ITF, Polypeptide P1.B, hP1.B<br/>Recombinant Human Trefoil Factor 3 (TFF3)

Gene ID

7033

Accession Number

Q07654

Organism

Human

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Purity

>95% as determined by SDS-PAGE

Solubility

Reconstitute at 100 μg/mL in sterile PBS

Function

The ED(50) was determined by the dose-dependent proliferation of KTC cells and was found to be <0.5ng/mL.

Molecular Weight

6.8

Shipping Conditions

Ambient Temperature

Storage Conditions

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.