Recombinant Human TFF2

Found in the gastrointestinal tract, the three Trefoil proteins, TFF1, 2, and 3 have been shown to play an important role in intestinal mucosal defence and repair. Specifically, TFF2 has been shown to inhibit gastrointestinal motility and secretion of the gastric acid.

Product Specifications

CAS Number

9000-83-3

Gene Name

TFF2

Gene Aliases

TFF2, Spasmolysin, Spasmolytic polypeptide, SP<br/>Recombinant Human Trefoil Factor 2 (TFF2)

Gene ID

7032

Accession Number

Q03403

Organism

Human

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method

Purity

>95% as determined by SDS-PAGE

Solubility

Reconstitute at 100 μg/mL in sterile PBS

Function

The ED(50) was determined by the dose-dependent proliferation of immortalized human pancreatic cells and was found to be <5ng/mL.

Molecular Weight

12.3

Shipping Conditions

Ambient Temperature

Storage Conditions

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.