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Recombinant Human TFF1

Found in the gastrointestinal tract, the three Trefoil proteins, TFF1, 2, and 3 have been shown to play an important role in intestinal mucosal defence and repair. Specifically, TFF1 is essential for normal differentiation of the antral and pyloric gastric mucosa and functions as a gastric-specific tumor suppressor gene.

Product Specifications

CAS Number

9000-83-3

Gene Name

TFF1

Gene Aliases

TFF1, Breast cancer estrogen-inducible protein, BCEI, PNR-2, Polypeptide P1.A, Protein pS2<br/>Recombinant Human Trefoil Factor 1 (TFF1)

Gene ID

7031

Accession Number

P04155

Organism

Human

Source

E. coli

Concentration

< 1.0 EU/μg of recombinant protein as determined by the LAL method.

Purity

>95% as determined by SDS-PAGE

Solubility

Reconstitute at 100 μg/mL in sterile PBS

Function

The ED(50) was determined by the dose-dependent proliferation of MCF7 cells and was found to be &lt;0.5ng/mL.

Molecular Weight

6.9

Shipping Conditions

Ambient Temperature

Storage Conditions

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Appearance

Lyophilized Powder

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS

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