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Recombinant Human TARC (CCL17)

Thymus and activation-regulated chemokine (TARC) is a recently identified CC chemokine that is expressed constitutively in the thymus and transiently in stimulated peripheral blood mononuclear cells. TARC functions as a selective chemoattractant for T cells that express a class of receptors binding TARC with high affinity and specificity. The chemokine TARC is a ligand for the chemokine receptor CCR4 expressed on CD4 Th2 cells.

Product Specifications

CAS Number

9000-83-3

Gene Name

CCL17

Gene Aliases

CC chemokine TARC, Small-inducible cytokine A17, C-C motif chemokine 17, chemokine 17, CCL17, ABCD-2, SCYA17, TARC<br/>Recombinant Human Thymus and Activation-Regulated Chemokine (CCL17)

Gene ID

6361

Accession Number

Q92583

Organism

Human

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Purity

>95% as determined by SDS-PAGE

Solubility

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Function

Determined by its ability to chemoattract human T cells using a concentration range of 2-40 ng/mL.

Molecular Weight

8

Shipping Conditions

Ambient Temperature

Storage Conditions

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Appearance

Lyophilized Powder

Formulation

Recombinant TARC was lyophilized from a 0.2 μm filtered 20 mM PB,100 mM NaCl solution pH 7.5.

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