Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Recombinant Human RANTES (CCL5)

RANTES belongs to the family of chemotactic cytokines known as chemokines and is expressed by an early response gene. The synthesis of RANTES is induced by TNF-alpha and IL-1-alpha. RANTES is chemotactic for T cells, human eosinophils and basophils and plays an active role in recruiting leukocytes into inflammatory sites. RANTES also activates eosinophils to release eosinophilic cationic protein while being a potent activator of oxidative metabolism specific for eosinophils. RANTES increases the adherence of monocytes to endothelial cells and selectively supports the migration of monocytes and T lymphocytes expressing the cell surface markers CD4 and UCHL1.

Product Specifications

Gene Name

CCL5

Gene Aliases

Regulation upon Activation Normal T cell Express Sequence, CCL5, SIS-delta, C-C motif chemokine 5, EoCP, Eosinophil chemotactic cytokine, Small-inducible cytokine A5, T cell-specific protein P228, TCP228, T-cell-specific protein RANTES, D17S136E, SCYA5

Gene ID

6352

Accession Number

P13501

Organism

Human

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method

Purity

>95% as determined by SDS-PAGE

Solubility

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Function

Determined by its ability to chemoattract human blood monocytes using a concentration range of 1-10 ng/mL.

Molecular Weight

9

Shipping Conditions

Ambient Temperature

Storage Conditions

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Appearance

Lyophilized Powder

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS

CAS Number

9000-83-3

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Mouse Monoclonal CD40/TNFRSF5 Antibody (82111) [mFluor Violet 500 SE]
FAB6321MFV500 0.1 mL

Mouse Monoclonal CD40/TNFRSF5 Antibody (82111) [mFluor Violet 500 SE]

Ask
View Details
MUC19 Protein Lysate (Human) with C-Ha Tag
31132031 100 μg

MUC19 Protein Lysate (Human) with C-Ha Tag

Ask
View Details
FDPS (Farnesyl Pyrophosphate Synthase, FPP Synthase, FPS, Farnesyl Diphosphate Synthase, FPS, KIAA1293) (HRP)
MBS6152489-01 0.1 mL

FDPS (Farnesyl Pyrophosphate Synthase, FPP Synthase, FPS, Farnesyl Diphosphate Synthase, FPS, KIAA1293) (HRP)

Ask
View Details
FDPS (Farnesyl Pyrophosphate Synthase, FPP Synthase, FPS, Farnesyl Diphosphate Synthase, FPS, KIAA1293) (HRP)
MBS6152489-02 5x 0.1 mL

FDPS (Farnesyl Pyrophosphate Synthase, FPP Synthase, FPS, Farnesyl Diphosphate Synthase, FPS, KIAA1293) (HRP)

Ask
View Details
Anti-Thioredoxin / TRX (6C10)
YF-MA15994 100 ug

Anti-Thioredoxin / TRX (6C10)

Ask
View Details