Recombinant Human Prolactin (PRL)

Synthesized primarily by the pituitary gland, prolactin is a neuroendocrine hormone that functions to promote and maintain lactation and has also been shown to play a role in breast cancer development, regulation of reproductive function and immune-regulation. While Human prolactin shares only 60% and 63% amino acid sequence identity with mouse and rat prolactin, respectively, the human prolactin receptor can be activated by Rat PRL. abm's Recombinant Human PRL is a single, non-glycosylated polypeptide chain with a molecular mass of 23 KDa.

Product Specifications

CAS Number

9000-83-3

Gene Name

PRL

Gene Aliases

Luterotropic hormone, Lutetropin, Mammotropin, PRL

Gene ID

5617

Accession Number

P01236

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Purity

>95% as determined by SDS-PAGE

Solubility

It is recommended to reconstitute lyophilized PRL in sterile distilled water to no less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Function

Determined by its ability to induce the proliferation of rat Nb2-11 cells in the concentration range of 0.1-1.0 ng/ml.

Molecular Weight

Shipping Conditions

Ambient Temperature

Storage Conditions

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.