Recombinant Human OPG (TNFRSF11B)

A member of the TNF superfamily, OPG is expressed in many different tissues, including the heart, liver, lung and bone marrow although it main role is to mediate bone density. When expressed, the protein may form dimers or stay in its monomeric form. The three dimensional structure of OPG can be divided into seven distinct domains, four of which correspond to the extracellular region of TNFR proteins and constitutes the soluble form of OPG.

Product Specifications

CAS Number

9000-83-3

Gene Name

TNFRSF11B

Gene Aliases

OCIF, Tumor necrosis factor receptor superfamily member 11B, TNFRSF11B, Osteoprotegerin, TNFRSF11B, TR1<br/>Recombinant Human Osteoclastogenesis Inhibitory Factor (TNFRSF11B)

Gene ID

4982

Accession Number

O00300

Organism

Human

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Purity

>95% as determined by SDS-PAGE

Solubility

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Function

N.A.

Molecular Weight

Shipping Conditions

Ambient Temperature

Storage Conditions

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.