What is the catalog number for Recombinant Human NRG1?

The catalog number for Recombinant Human NRG1 is Z101629.

What sizes are available for Recombinant Human NRG1?

Recombinant Human NRG1 is available in the following size(s): 1 mg.

Is Recombinant Human NRG1 in stock?

Recombinant Human NRG1 is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant Human NRG1

Neuregulins are EGF-like growth and differentiation factors that signal through tyrosine kinase receptors of the ErbB family. The ErbB2 and ErbB4 receptors cooperate in transmission of neuregulin-1 signals in the heart, whereas ErbB2 and ErbB3 cooperate in neural crest cells.

Product Specifications

CAS Number

9000-83-3

Gene Name

NRG1

Gene Aliases

Acetylcholine receptor-inducing activity, ARIA, Breast cancer cell differentiation factor p45, Glial growth factor, Heregulin, HRG, Neu differentiation factor, Sensory and motor neuron-derived factor<br/>Recombinant Human Neuregulin-1 Beta (NRG1)

Gene ID

3084

Accession Number

Q02297

Organism

Human

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Purity

>95% as determined by SDS-PAGE

Solubility

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Function

The ED(50) was determined by the dose-dependent proliferation of human MCF-7 cells was found to be < 0.3 ng/mL, corresponding to a specific activity of 2.0 x 10^6 Units/mg.

Molecular Weight

7

Shipping Conditions

Ambient Temperature

Storage Conditions

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.