Recombinant Human NRG1
Neuregulins are EGF-like growth and differentiation factors that signal through tyrosine kinase receptors of the ErbB family. The ErbB2 and ErbB4 receptors cooperate in transmission of neuregulin-1 signals in the heart, whereas ErbB2 and ErbB3 cooperate in neural crest cells.
Product Specifications
Gene Name
NRG1
Gene Aliases
Acetylcholine receptor-inducing activity, ARIA, Breast cancer cell differentiation factor p45, Glial growth factor, Heregulin, HRG, Neu differentiation factor, Sensory and motor neuron-derived factor<br/>Recombinant Human Neuregulin-1 Beta (NRG1)
Gene ID
3084
Accession Number
Q02297
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
The ED(50) was determined by the dose-dependent proliferation of human MCF-7 cells was found to be < 0.3 ng/mL, corresponding to a specific activity of 2.0 x 10^6 Units/mg.
Molecular Weight
7
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Recombinant Neuregulin-1 was lyophilized from a 0.2 μm filtered 10mM PB, pH 7.0, containing 2% mannitol, 0.5% HSA.
CAS Number
9000-83-3
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![PGAM4 Mouse Monoclonal Antibody [Clone 1C5]](https://cdn.genprice.uk/genprice/genprice3.png)
![Mouse Monoclonal MMP-1 Antibody (6A5) [Alexa Fluor 405]](https://cdn.genprice.uk/genprice/genprice4.png)
