Recombinant Human MMP2
MMP-2 belongs to a family of endoproteases which need calcium and zinc in order to exert their catalytic capability (extracellular matrix remodeling). The elevated expression of these enzymes has been linked to many degenerative disorders, such as arthritis, cancer metastasis and skeletal growth-plate disorders. It has been shown that MMP-2 associates with many connective tissue cells as well as neutrophils, macrophages and monocytes.
Product Specifications
CAS Number
9000-83-3
Gene Name
MMP2
Gene Aliases
MMP-2, 72 kDa type IV collagenase, 72 kDa gelatinase, Gelatinase A, TBE-1<br/>Recombinant Human Matrix Metalloproteinase-2 (MMP2)
Gene ID
4313
Accession Number
P08253
Organism
Human
Source
E. coli
Concentration
< 1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
N.A.
Function
The ED(50) was determined by the dose-dependent proliferation of immortalized human pulmonary fibroblasts cells and was found to be <0.05ng/mL.
Molecular Weight
62
Shipping Conditions
Ambient Temperature
Storage Conditions
Appearance
Lyophilized Powder
Formulation
Supplied as a 0.2 μm filtered solution in Tris, CaCl2, NaCl and Brij35
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