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Recombinant Human MIP-1 beta (CCL4L1)

MIP-1-beta is one of the peptides of Macrophage Inflammatory Protein-1 that is produced by macrophages following their stimulation with bacterial endotoxins. MIP-1-beta causes local inflammatory responses, and induces superoxide production by neutrophils. The aforementioned activates of MIP-1-beta are exerted following its binding to CCR5.

Product Specifications

CAS Number

9000-83-3

Gene Name

CCL4L1

Gene Aliases

C-C motif chemokine 4-like, G-26, T-lymphocyte-secreted protein HC21, Lymphocyte activation gene 1 protein, LAG-1, MIP-1-beta, PAT 744, Protein H400, SIS-gamma, Small-inducible cytokine A4, T-cell activation protein 2, ACT-2, MIP1B, SCYA4<br/>Recombinant Human Lymphocyte Activation Gene-1 (CCL4L1)

Gene ID

388372

Accession Number

Q8NHW4

Organism

Human

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Purity

>95% as determined by SDS-PAGE

Solubility

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Function

Determined by its ability to chemoattract human blood monocytes using a concentration range of 2-10 ng/mL.

Molecular Weight

8.1

Shipping Conditions

Ambient Temperature

Storage Conditions

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Appearance

Lyophilized Powder

Formulation

Lyophilized from a 0.2 μm filtered PBS solution

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