Recombinant Human MIP-1 beta (CCL4L1)
MIP-1-beta is one of the peptides of Macrophage Inflammatory Protein-1 that is produced by macrophages following their stimulation with bacterial endotoxins. MIP-1-beta causes local inflammatory responses, and induces superoxide production by neutrophils. The aforementioned activates of MIP-1-beta are exerted following its binding to CCR5.
Product Specifications
CAS Number
9000-83-3
Gene Name
CCL4L1
Gene Aliases
C-C motif chemokine 4-like, G-26, T-lymphocyte-secreted protein HC21, Lymphocyte activation gene 1 protein, LAG-1, MIP-1-beta, PAT 744, Protein H400, SIS-gamma, Small-inducible cytokine A4, T-cell activation protein 2, ACT-2, MIP1B, SCYA4<br/>Recombinant Human Lymphocyte Activation Gene-1 (CCL4L1)
Gene ID
388372
Accession Number
Q8NHW4
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
Determined by its ability to chemoattract human blood monocytes using a concentration range of 2-10 ng/mL.
Molecular Weight
8.1
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.
Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered PBS solution
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