Recombinant Human MIA
MIA is a secreted, regulatory protein produced mainly by chondrocytes and malignant melanoma cells. This protein induces the metastasis of cancer cells by indirectly causing the detachment of melanoma cells from the surrounding extracellular matrix. MIA levels are now measured and used as a diagnostic tool for melanoma metastasis and rheumatoid arthritis.
Product Specifications
CAS Number
9000-83-3
Gene Name
MIA
Gene Aliases
Melanoma inhibitory activity protein, Cartilage-derived retinoic acid-sensitive protein, CD-RAP<br/>Recombinant Human Melanoma Derived Growth Regulatory Protein (MIA)
Gene ID
8190
Accession Number
Q16674
Organism
Human
Source
E. coli
Concentration
< 1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
Reconstitute at 100 μg/mL in sterile PBS
Function
N.A.
Molecular Weight
12.4
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.
Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS
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