Recombinant Human MEC (CCL28)
The mucosa-associated epithelial chemokine CCL28 is a common mucosal chemokine which is constitutively expressed by epithelial cells in most mucosal sites. Both CCL28 and CCL25 have recently been shown to be essential for lymphocyte migration to gastrointestinal tissues. CCL28 attracts IgA ASC, but not IgG or IgM ASC, from both intestinal and extraintestinal mucosal tissue, while CCL25 preferentially attracts IgA ASC from the small intestine and its draining lymphoid tissues, as well as alpha-4-beta-7(+) T cells.
Product Specifications
CAS Number
9000-83-3
Gene Name
CCL28
Gene Aliases
Gene ID
56477
Accession Number
Q9NRJ3
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
Function
Determined by the ability to chemoattract human lymphocytes using a concentration range of 2-10 ng/mL.
Molecular Weight
12
Shipping Conditions
Ambient Temperature
Storage Conditions
Appearance
Lyophilized Powder
Formulation
Recombinant CCL-28 was lyophilized from PBS pH 7.4.
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