Recombinant Human MANF
MANF is a neurotrophic factor found mainly in central nervous tissues where it may remain localized to the endoplasmic reticulum and in the Golgi apparatus, or secreted. It has been shown that MANF plays an important role in protecting cells against tunicamycin and thapsigargin-induced cell death. Without MANF, cells become increasingly vulnerable to the aforementioned drugs. Also, MANF is structurally homologous to CDNF.
Product Specifications
Gene Name
MANF
Gene Aliases
Arginine-rich protein, Protein ARMET, ARP<br/>Recombinant Human Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
Gene ID
7873
Accession Number
P55145
Organism
Human
Source
E. coli
Concentration
< 1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
Reconstitute at 200 μg/mL in PBS
Function
N.A.
Molecular Weight
18.4
Shipping Conditions
Ambient Temperature
Storage Conditions
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS
CAS Number
9000-83-3
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