Recombinant Human Lymphotactin (XCL1)

XCL1, also known as lymphotactin or ATAC, is the sole member of the C subgroup of chemokines, and more importantly, is produced mainly by activated CD8 T cells (and to a lesser extent by natural killer and mast cells). The chemotactic activity of XCL1 is restricted to lymphocytes and has no effect on monocytes.

Product Specifications

CAS Number

9000-83-3

Gene Name

XCL1

Gene Aliases

ATAC, C motif chemokine 1, Cytokine SCM-1, Lymphotaxin, SCM-1-alpha, Small-inducible cytokine C1, XC chemokine ligand 1, XCL1, LTN, SCYC1

Gene ID

6375

Accession Number

P47992

Organism

Human

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Purity

>95% as determined by SDS-PAGE

Solubility

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Function

Activity was determined by the ability to induce chemotaxis of human T-cells at concentrations ranging between 50-100 ng/ml.

Molecular Weight

Shipping Conditions

Ambient Temperature

Storage Conditions

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.