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Recombinant Human Lymphotactin (XCL1)

XCL1, also known as lymphotactin or ATAC, is the sole member of the C subgroup of chemokines, and more importantly, is produced mainly by activated CD8 T cells (and to a lesser extent by natural killer and mast cells). The chemotactic activity of XCL1 is restricted to lymphocytes and has no effect on monocytes.

Product Specifications

Gene Name

XCL1

Gene Aliases

ATAC, C motif chemokine 1, Cytokine SCM-1, Lymphotaxin, SCM-1-alpha, Small-inducible cytokine C1, XC chemokine ligand 1, XCL1, LTN, SCYC1

Gene ID

6375

Accession Number

P47992

Organism

Human

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Purity

>95% as determined by SDS-PAGE

Solubility

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Function

Activity was determined by the ability to induce chemotaxis of human T-cells at concentrations ranging between 50-100 ng/ml.

Molecular Weight

10

Shipping Conditions

Ambient Temperature

Storage Conditions

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Appearance

Lyophilized Powder

Formulation

Recombinant Lymphotactin was lyophilzed from 0.2μm filtered PBS, pH 7.0.

CAS Number

9000-83-3

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