What is the catalog number for Recombinant Human LTA?

The catalog number for Recombinant Human LTA is Z100867.

What sizes are available for Recombinant Human LTA?

Recombinant Human LTA is available in the following size(s): 100 µg.

Is Recombinant Human LTA in stock?

Recombinant Human LTA is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant Human LTA

TNF-beta is a potent mediator of inflammatory and immune responses. It belongs to the TNF family of ligands and signals through TNFR1 and TNFR2. TNF-beta is produced by activated T and B lymphocytes, and has similar activities to TNF-alpha. Like TNF-alpha, TNF-beta is involved in the regulation of various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNF-beta is secreted as a soluble polypeptide, but can form heterotrimers with lymphotoxin-beta, which effectively anchors the TNF-beta to the cell surface. TNF-beta is cytotoxic to a wide range of tumor cells.

Product Specifications

CAS Number

9000-83-3

Gene Name

LTA

Gene Aliases

Tumor necrosis factor ligand superfamily member 1, TNFSF1, Lymphotoxin-alpha, LT-alpha, LTA <br/>Recombinant Human Tumor Necrosis Factor Beta (LTA)

Gene ID

4049

Accession Number

P01374

Organism

Human

Source

E. coli

Purity

>95% as determined by SDS-PAGE

Solubility

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Function

The ED(50) was measured in a cytotoxicity assay using mouse L929 cells in the presence of the metabolic inhibitor actinomycin, and was determined to be less than 0.1 ng/mL.