Recombinant Human Leptin (LEP)
Leptin is a cytokine found in the adipose tissue of animals (Leptin mRNA is restricted to the adipose tissue). Leptin has been shown to suppress appetite, increase thermogenesis and reduce body weight, food consumption and plasma glucose levels.
Product Specifications
Gene Name
LEP
Gene Aliases
OB, Obese protein, Obesity factor
Gene ID
3952
Accession Number
P41159
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method
Purity
>95% as determined by SDS-PAGE
Solubility
Reconstitute at 1 mg/mL in sterile 20 mM Tris-HCI (pH 8.0).
Function
The ED(50) was determined by the dose-dependent proliferation of human umbilical vein endothelial cells and was found to be <0.5ng/mL.
Molecular Weight
16.4
Shipping Conditions
Ambient Temperature
Storage Conditions
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered solution in Tris-HCl and NaCl.
CAS Number
9000-83-3
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