What is the catalog number for Recombinant Human IP-10 (CXCL10)?

The catalog number for Recombinant Human IP-10 (CXCL10) is Z100579.

What sizes are available for Recombinant Human IP-10 (CXCL10)?

Recombinant Human IP-10 (CXCL10) is available in the following size(s): 1 mg.

Is Recombinant Human IP-10 (CXCL10) in stock?

Recombinant Human IP-10 (CXCL10) is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant Human IP-10 (CXCL10)

IP-10 shows homology to PF-4 (platelet factor-4) and belongs to the family of chemotactic cytokines known as chemokines. The receptor for IP-10 is CXCR3. IP-10 has been shown to bind to the virus-encoded viroceptor M3. The expression of IP-10 from a variety of cells, including monocytes, endothelial cells, keratinocytes, and fibroblasts, is induced by IFN-gamma and TNF-alpha. Human neutrophils produce IP-10 in response to IFN- gamma in combination with either TNF-alpha or bacterial lipopolysaccharides. IP-10 probably also plays a role in regulation of the growth of immature hematopoietic progenitor cells. It has been shown to suppress in vitro colony formation of highly enriched cells expressing the cell surface marker CD34 in the presence of SCF, GM-CSF, or SCF and EPO, but not in their absence with the exception of SCF.

Product Specifications

CAS Number

9000-83-3

Gene Name

CXCL10

Gene Aliases

CXCL10, C-X-C motif chemokine 10, 10 kDa interferon gamma-induced protein, Gamma-IP10, Small-inducible cytokine B10, IP10

Gene ID

3627

Accession Number

P02778

Organism

Human

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Purity

>95% as determined by SDS-PAGE

Solubility

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Function

Determined by its ability to chemoattract human T-Lymphocytes using a concentration of 10-50 ng/mL.

Molecular Weight

9

Shipping Conditions

Ambient Temperature

Storage Conditions

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.