Recombinant Human IL36A

IL-1 epsilon is an actively secreted member of the IL-1 family of cytokines. It is mainly expressed in tissues with epithelial cells and in psoriatic plaques, as well as by monocytes, B cells and T cells. IL-1 epsilon has been shown to signal through the IL-Rrp2 receptor which is primarily expressed on certain denditic cells, and to act as an agonist of NF-kappaB which then stimulates the inflammatory response in bronchial epithelial cells.

Product Specifications

CAS Number

9000-83-3

Gene Name

IL36A

Gene Aliases

IL-1 Epsilon, FIL1 epsilon, Interleukin-1 family member 6, IL-1F6, IL-36 gamma, IL-1F, IL-1H1<br/>Recombinant Human Interleukin-36 alpha (IL36A)

Gene ID

27179

Accession Number

Q9UHA7

Organism

Human

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Purity

>95% as determined by SDS-PAGE

Solubility

Reconstitute at 10 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin

Function

N.A.

Molecular Weight

17.4

Shipping Conditions

Ambient Temperature

Storage Conditions

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.