Recombinant Human IL22

Originally identified as a gene induced by IL-9 in mouse T cells and mast cells, IL-22 is a member of the IL-10 family of cytokines. IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the pancreas and liver. The IL-22 receptor complex consists of two receptor subunits, IL-22R and IL-10R-beta that belong to the class II cytokine receptor family. Recombinant human IL-22 is a non-disulfide-linked homodimeric protein.

Product Specifications

CAS Number

9000-83-3

Gene Name

IL22

Gene Aliases

IL-22, IL-TIF, Cytokine Zcyto18, IL-10-related T cell-derived-inducible factor, ILTIF, ZCYTO18<br/>Recombinant Human Interleukin-22 (IL22)

Gene ID

50616

Accession Number

Q9GZX6

Organism

Human

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Purity

>95% as determined by SDS-PAGE

Solubility

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Function

Activity was determined by the ability to inhibit growth of human A549 cancer cells at concentrations ranging between 50-100 ng/mL.

Molecular Weight

Shipping Conditions

Ambient Temperature

Storage Conditions

Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.