What is the catalog number for Recombinant Human IL17F?

The catalog number for Recombinant Human IL17F is Z102435.

What sizes are available for Recombinant Human IL17F?

Recombinant Human IL17F is available in the following size(s): 25 µg.

Is Recombinant Human IL17F in stock?

Recombinant Human IL17F is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant Human IL17F

Interleukin 17F is a disulfide-linked homodimeric protein belonging to the IL-17 family of proinflammatory cytokines. Members belonging to this family share conserved features of cysteine-knot structures but differ in their N-terminal regions. The T-helper cell produced IL-17 family is inducible by IL15 and IL23, and IL17F induces T-cell and PBMC activation and proliferation. It also performs cartilage matrix turnover and angiogenesis prevention. Out of the IL-17 family, IL17F is the most homologous to IL17 and dimerizes in a way similar to that of nerve growth factors (NGF) and other neurotrophins.

Product Specifications

CAS Number

9000-83-3

Gene Name

IL17F

Gene Aliases

Cytokine ML-1

Gene ID

112744

Accession Number

Q96PD4

Organism

Human

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method

Purity

>95% as determined by SDS-PAGE

Solubility

A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Function

The ED50 is 8.0-40.0ng/mL as determined by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells

Molecular Weight

15.2

Shipping Conditions

Ambient Temperature

Storage Conditions

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.