Recombinant Human IGFBP7
IBP-7 is a secreted glycoprotein which mediates skeletal myogenesis by binding to IGF and inhibiting its ability to induce skeletal myoblast differentiation while maintaining a constant growth of myoblasts. It has been shown that IBP-7 suppresses growth of cancer cell lines through an IGF independent pathway.
Product Specifications
CAS Number
9000-83-3
Gene Name
IGFBP7
Gene Aliases
IBP-7, IGF-binding protein 7, IGFBP-7, IGFBP-rP1, MAC25 protein, PGI2-stimulating factor, Prostacyclin-stimulating factor, Tumor-derived adhesion factor, TAF, Angiomodulin, AGM<br/>Recombinant Human Insulin-Like Growth Factor Binding Protein 7 (IGFBP7)
Gene ID
3490
Accession Number
Q16270
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
Reconstitute at 100 μg/mL in sterile PBS
Function
Measured by its ability to bind CCL21 in a functional ELISA
Molecular Weight
26.7
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.
Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS
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