Recombinant Human GMFB
GMF-beta is a 17-kDa brain-specific protein that was isolated from bovine brain homogenate as a substance inducing the maturation of normal neurons as well as glial cells, and at first, it was considered to be a neurotrophic factor. The amino acid sequence of GMFB is highly conserved among many species, suggesting that it plays basic roles across many species. The expression of GMF-b is largely limited to the brain, especially the glial cells and some neurons. Schwann cells of the distal segment of the transected nerve express GMF-b, and this induction of GMF-b coincides with the temporal expression of nerve growth factor receptors in the cell.
Product Specifications
Gene Name
GMFB
Gene Aliases
GMF-beta, GMFB<br/>Recombinant Human Glia Maturation Factor Beta (GMFB)
Gene ID
2764
Accession Number
P60983
Organism
Human
Source
E. coli
Concentration
< 1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
Function
ED50 not determined.
Molecular Weight
15
Shipping Conditions
Ambient Temperature
Storage Conditions
Appearance
Lyophilized Powder
Formulation
Recombinant GMFB was lyophilized from a 0.2 μm filtered 20 mM PB,130 mM NaCl solution pH 7.5.
CAS Number
9000-83-3
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